Effects of Fruits of Barringtonia Racemosa Linn. on Human Polymorphonuclear Cell

نویسندگان

  • Sudha Patil
  • Mahesh Ramu Patil
  • Prabhakar Patil
  • Rohit Dixit
  • Rajesh C Sharma
چکیده

Address for Correspondence: Dr. Prabhakar Patil, Navodaya Medical College, Raichur, Karnataka, India. Mobile No. +919900346851. E-Mail: [email protected] Access this Article online Quick Response code Web site: 1,*3,4,5 Navodaya Medical College Raichur, Karnataka, India. 2 R.C. Patel College of Pharmacy, Shirpur, Dhule, Maharashtra, India. The objective of present study was to investigate Petroleum ether, ethyl acetate and hydroalcoholic extracts of B. racemosa fruits in vitro on human polymorphonuclear (PMN) cells to screen their effects on phagocytosis and chemotaxis. Ethyl acetate extract of B. racemosa fruits was found to be a stimulant of PMN cell phagocytosis of Nitroblue tetrazolium (NBT) dye and candida albicans. It also stimulated intracellur killing capacity of PMN cells. It was further found to increase the chemotaxis of human PMN cells. While, petroleum ether extract and hydroalcoholic extract were lesser active as far as these activities are concerned.

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تاریخ انتشار 2014